SCHEMBL31296414

SCHEMBL31296414

CCCCCc1cc(-c2ccccc2)c2c(c1C)CC(C(=O)OC)(C(=O)OC)C2

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 8/20 0.39
PPARA Q07869 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
TSHR P16473 1/20 0.36
CYP2C19 P33261 1/20 0.36
RARB P10826 1/20 0.36
CNR1 P21554 2/20 0.36
CNR2 P34972 2/20 0.36
SOAT1 P35610 2/20 0.36
BID P55957 3/20 0.35
MCL1 Q07820 3/20 0.35
BCL2L1 Q07817 2/20 0.35
BAK1 Q16611 2/20 0.35
KAT8 Q9H7Z6 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31296429 0.89 CNR2 (0.37) CHRM3PPARACNR1CNR2SOAT1
SCHEMBL31296495 0.83 MAOA (0.36) PPARAKDM4ECYP1A2CYP3A4CYP2D6
SCHEMBL31296419 0.82 MEN1 (0.37) PPARACYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL31296421 0.80 CNR2 (0.37) PPARAKDM4ECYP1A2CYP3A4CYP2D6
SCHEMBL31296449 0.76 CXCR5 (0.39) PPARAKDM4ECYP1A2CYP3A4CYP2D6
SCHEMBL31296498 0.75 MAOA (0.39) PPARACYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL31296472 0.74 SCN1A (0.37) KDM4ETSHR
SCHEMBL31296486 0.71
SCHEMBL31296456 0.71
SCHEMBL31296443 0.71 MEN1 (0.35) PPARAKDM4ECYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219681-A Method for synthesizing axial chiral organoboron compounds 合成化学暨分子生物学有限公司 2024-12-31 CN disclosed