SCHEMBL31296419

SCHEMBL31296419

CCCCCCCCc1cc(C)c2c(c1C)CC(C(=O)OC)(C(=O)OC)C2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
KMT2A Q03164 1/20 0.37
ALOX5 P09917 4/20 0.36
MAOA P21397 1/20 0.36
CNR2 P34972 3/20 0.35
PTGS2 P35354 3/20 0.35
PPARA Q07869 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
BID P55957 3/20 0.34
MCL1 Q07820 3/20 0.34
BCL2L1 Q07817 2/20 0.34
BAK1 Q16611 2/20 0.34
KAT8 Q9H7Z6 2/20 0.34
TYR P14679 1/20 0.34
PPARG P37231 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31296495 0.99 MAOA (0.36) MEN1ALDH1A1KMT2AALOX5MAOA
SCHEMBL31296486 0.86
SCHEMBL31296456 0.86
SCHEMBL31296421 0.82 CNR2 (0.37) MEN1ALDH1A1KMT2AMAOACNR2
SCHEMBL31296449 0.82 CXCR5 (0.39) PPARACYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL31296414 0.82 CHRM3 (0.39) CNR2PPARACYP1A2CYP3A4CYP2D6
SCHEMBL31296467 0.80 KDM4E (0.38) ALDH1A1CYP1A2CYP2C9
SCHEMBL31296472 0.79 SCN1A (0.37) MEN1ALDH1A1KMT2APTGS2
SCHEMBL31296484 0.78 GAA (0.34) ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL31296478 0.78 IDO1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219681-A Method for synthesizing axial chiral organoboron compounds 合成化学暨分子生物学有限公司 2024-12-31 CN disclosed