SCHEMBL31296449

SCHEMBL31296449

CCCCCc1cc(C)c2c(c1C)CC(C(=O)OC)(c1ccccc1)C2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR5 P32302 1/20 0.39
OPRM1 P35372 3/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
TSHR P16473 1/20 0.36
CYP2C19 P33261 1/20 0.36
OPRD1 P41143 2/20 0.36
OPRK1 P41145 2/20 0.36
ADRA1A P35348 2/20 0.36
PPARA Q07869 2/20 0.36
SLC22A1 O15245 1/20 0.36
SLC6A4 P31645 1/20 0.36
KCNH2 Q12809 1/20 0.36
KCNA3 P22001 1/20 0.35
ADRA1D P25100 1/20 0.35
BID P55957 3/20 0.35
MCL1 Q07820 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31296495 0.83 MAOA (0.36) KDM4ECYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL31296419 0.82 MEN1 (0.37) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL31296414 0.76 CHRM3 (0.39) KDM4ECYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL31296421 0.76 CNR2 (0.37) CXCR5KDM4ECYP1A2CYP3A4CYP2D6
SCHEMBL31296457 0.75 NR1H2 (0.39) KDM4E
SCHEMBL31296472 0.74 SCN1A (0.37) KDM4ETSHR
SCHEMBL31296463 0.73 ALDH1A1 (0.38) KDM4ECYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL31296485 0.73 HPGD (0.31)
SCHEMBL31296486 0.71
SCHEMBL31296456 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219681-A Method for synthesizing axial chiral organoboron compounds 合成化学暨分子生物学有限公司 2024-12-31 CN disclosed