Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26623811 | 1.00 | L3MBTL1 (0.49) | L3MBTL1PKMHPGDTSHRALDH1A1 | |
| SCHEMBL31535836 | 0.80 | TP53 (0.40) | L3MBTL1PKMHPGDTSHRALDH1A1 | |
| SCHEMBL6377477 | 0.79 | LMNA (0.48) | L3MBTL1HPGDTSHRALDH1A1RAB9A | |
| SCHEMBL1806643 | 0.79 | L3MBTL1 (0.56) | L3MBTL1PKMHPGDTSHRALDH1A1 | |
| SCHEMBL31525412 | 0.78 | MAPT (0.50) | L3MBTL1PKMHPGDTSHRALDH1A1 | |
| SCHEMBL23833456 | 0.78 | POLB (0.46) | L3MBTL1PKMHPGDTSHRALDH1A1 | |
| SCHEMBL20680345 | 0.78 | ALDH1A1 (0.41) | L3MBTL1PKMHPGDALDH1A1RAB9A | |
| SCHEMBL20304607 | 0.78 | MAPT (0.43) | L3MBTL1PKMHPGDTSHRALDH1A1 | |
| SCHEMBL26693895 | 0.78 | GPBAR1 (0.42) | L3MBTL1PKMHPGDALDH1A1RAB9A | |
| SCHEMBL30642583 | 0.78 | HPGD (0.47) | L3MBTL1PKMHPGDTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119137107-A | Macrocyclic inhibitors of ATP citrate lyase | 艾斯柏伦治疗公司 | 2024-12-13 | — | — | CN | disclosed |