Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3854546 | 1.00 | HPGD (0.48) | HPGDALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL30695503 | 0.82 | HPGD (0.70) | HPGDALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL3855655 | 0.79 | KMT2A (0.50) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3711270 | 0.76 | PIK3CA (0.61) | HPGDALDH1A1LMNADRD2TBXA2R | |
| SCHEMBL3289235 | 0.76 | KDM4E (0.47) | HPGDALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL730969 | 0.75 | LMNA (0.59) | HPGDALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL30931811 | 0.75 | LMNA (0.59) | HPGDALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL20872587 | 0.75 | L3MBTL1 (0.48) | HPGDALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL29628550 | 0.75 | L3MBTL1 (0.48) | HPGDALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL31726517 | 0.75 | L3MBTL1 (0.54) | HPGDALDH1A1TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119137107-A | Macrocyclic inhibitors of ATP citrate lyase | 艾斯柏伦治疗公司 | 2024-12-13 | — | — | CN | disclosed |