SCHEMBL31297352

SCHEMBL31297352

C=CCC1=NOc2ccccc2C=C1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9933267 0.77 KDM4E (0.33) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL28760203 0.75 TDP1 (0.32) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL5079126 0.72 AKR1B1 (0.38) KDM4EMEN1MAPTKMT2A
SCHEMBL6190907 0.71 LMNA (0.34) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL9935511 0.71 KDM4E (0.36) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL7098395 0.70 MAPT (0.38) KDM4EMEN1ALDH1A1MAPTKMT2A
Hydrochloric Acid SCHEMBL8206694 0.70 LMNA (0.33) KDM4EMEN1ALDH1A1MAPTKMT2A
Hydrochloric Acid SCHEMBL8205122 0.70 LMNA (0.33) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL8205903 0.68 HSD17B10 (0.36) KDM4EALDH1A1MAPT
Oxalic Acid SCHEMBL8205203 0.68 MEN1 (0.32) KDM4EMEN1ALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119143652-A Chiral 2-bit disubstituted indoline compound and synthetic method and application thereof 山东大学 2024-12-17 CN claimed
CN-119143652-B Chiral 2-bit disubstituted indoline compound and synthetic method and application thereof 山东大学 2025-11-28 CN disclosed
CN-119143652-A Chiral 2-bit disubstituted indoline compound and synthetic method and application thereof 山东大学 2024-12-17 CN disclosed
CN-119143652-A Chiral 2-bit disubstituted indoline compound and synthetic method and application thereof 山东大学 2024-12-17 CN disclosed