Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6188489 | 0.86 | SMN1; SMN2 (0.41) | HSD17B10ALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL5079126 | 0.82 | AKR1B1 (0.38) | HPGDKDM4EMAPTPOLBGAA | |
| SCHEMBL6190907 | 0.81 | LMNA (0.34) | ALDH1A1MAPK1KDM4EMAPTTRPA1 | |
| Hydrochloric Acid SCHEMBL8205122 | 0.79 | LMNA (0.33) | ALDH1A1MAPK1KDM4EMAPTTRPA1 | |
| Hydrochloric Acid SCHEMBL8206938 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MAPK1SMN1; SMN2KDM4EMAPT | |
| Oxalic Acid SCHEMBL8205203 | 0.77 | MEN1 (0.32) | ALDH1A1MAPK1KDM4EMAPTTRPA1 | |
| SCHEMBL9933267 | 0.75 | KDM4E (0.33) | ALDH1A1KDM4EMAPT | |
| SCHEMBL4563591 | 0.72 | LMNA (0.40) | MAPK1SMN1; SMN2TRPA1P2RX4NPSR1 | |
| SCHEMBL28760203 | 0.72 | TDP1 (0.32) | ALDH1A1KDM4EMAPT | |
| SCHEMBL11660750 | 0.71 | HPGD (0.46) | ALDH1A1MAPK1HPGDSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979227-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998047882-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-29 | — | — | WO | disclosed |