Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 4/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | HTR1D | P28221 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31297358 | 0.83 | LMNA (0.36) | L3MBTL1LMNAHTTNPSR1BACE1 | |
| SCHEMBL31297364 | 0.81 | MEN1 (0.33) | L3MBTL1LMNAHTTNPSR1 | |
| SCHEMBL31297363 | 0.72 | AR (0.41) | L3MBTL1SIGMAR1HTR5AADAM17 | |
| SCHEMBL31297361 | 0.71 | KDM1A (0.40) | KDM1ASIGMAR1HTR2AHTR2CHTR7 | |
| SCHEMBL31297362 | 0.71 | AKR1B1 (0.39) | LMNAHTT | |
| SCHEMBL31297356 | 0.70 | AHR (0.38) | AHRADRA2AADRA2BADRA2CDRD4 | |
| SCHEMBL31297357 | 0.69 | OPRM1 (0.32) | L3MBTL1LMNAHTTNPSR1 | |
| SCHEMBL31297355 | 0.65 | KMT2A (0.32) | KDM1A | |
| SCHEMBL28165119 | 0.62 | SIGMAR1 (0.40) | KDM1ARCOR1SIGMAR1HTR2CHTR2B | |
| SCHEMBL24219873 | 0.62 | AHR (0.42) | PGRAHRBACE1ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119143652-A | Chiral 2-bit disubstituted indoline compound and synthetic method and application thereof | 山东大学 | 2024-12-17 | — | — | CN | disclosed |