Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.33 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | PRKCI | P41743 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31297716 | 0.85 | CCNC (0.44) | MAPK1JMJD6CCNCCDK8PRKCI | |
| SCHEMBL31297732 | 0.84 | KDM4E (0.42) | MAPK1ALDH1A1HPGDPRKCI | |
| SCHEMBL31297599 | 0.81 | CCNC (0.32) | CCNCCDK8 | |
| SCHEMBL31297555 | 0.80 | MAPK1 (0.51) | MAPK1PTK2ALDH1A1PRKCI | |
| SCHEMBL31297682 | 0.77 | ALDH1A1 (0.34) | ALDH1A1HPGDHSD17B10PRKCI | |
| SCHEMBL31297597 | 0.75 | MAPK1 (0.33) | MAPK1PTK2CCNCCDK8 | |
| SCHEMBL14405050 | 0.73 | DYRK1A (0.43) | MAPK1JMJD6ADRA1A | |
| SCHEMBL31324862 | 0.72 | CCNC (0.47) | MAPK1PTK2CCNCCDK8HPGD | |
| SCHEMBL31297659 | 0.72 | MAPK1 (0.33) | MAPK1CCNCCDK8PRKCI | |
| SCHEMBL31297632 | 0.71 | SMN1; SMN2 (0.43) | MAPK1PTK2ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735114-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | Masarykova Univerzita (CZ) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025002491-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | MASARYKOVA UNIVERZITA (CZ) | 2025-01-02 | — | — | WO | disclosed |
| EP-4483954-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | Masarykova Univerzita (CZ) | 2025-01-01 | — | — | EP | disclosed |