Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31297716 | 0.81 | CCNC (0.44) | SMN1; SMN2KMT2ABRAFMAPK14MAPT | |
| SCHEMBL31297732 | 0.81 | KDM4E (0.42) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| SCHEMBL31297599 | 0.77 | CCNC (0.32) | — | |
| SCHEMBL31297600 | 0.77 | MAPK1 (0.35) | ALDH1A1HPGDHSD17B10PRKCI | |
| SCHEMBL31297632 | 0.76 | SMN1; SMN2 (0.43) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| SCHEMBL2148390 | 0.74 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| SCHEMBL31297604 | 0.72 | CYP19A1 (0.46) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| SCHEMBL31297597 | 0.72 | MAPK1 (0.33) | SMN1; SMN2BRAFMAPTDYRK1AFYN | |
| SCHEMBL31324862 | 0.69 | CCNC (0.47) | KDM4EHPGDSMN1; SMN2DYRK1AGRM5 | |
| SCHEMBL15072164 | 0.68 | KMT2A (0.50) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735114-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | Masarykova Univerzita (CZ) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025002491-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | MASARYKOVA UNIVERZITA (CZ) | 2025-01-02 | — | — | WO | disclosed |
| EP-4483954-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | Masarykova Univerzita (CZ) | 2025-01-01 | — | — | EP | disclosed |