Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3125821 | 0.84 | MEN1 (0.32) | ALDH1A1NPC1TP53PKM | |
| SCHEMBL826084 | 0.80 | KCNA5 (0.39) | TDP2ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL3121500 | 0.78 | ALDH1A1 (0.42) | ALDH1A1HPGDALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL3119020 | 0.73 | ALDH1A1 (0.60) | ALDH1A1HPGDALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL3124832 | 0.72 | GRM5 (0.35) | ALDH1A1HPGDHSD17B10SMN1; SMN2KCNA5 | |
| SCHEMBL1283403 | 0.70 | KCNA5 (0.35) | ALDH1A1KCNA5LMNAKDM4E | |
| SCHEMBL3129790 | 0.69 | MEN1 (0.35) | ALDH1A1SMN1; SMN2NPC1KDM4E | |
| SCHEMBL4719479 | 0.69 | TP53 (0.38) | ALDH1A1HSD17B10SMN1; SMN2NPC1TP53 | |
| SCHEMBL3125826 | 0.69 | KDM4E (0.35) | ALDH1A1SMN1; SMN2NPC1KDM4E | |
| SCHEMBL3130676 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | disclosed |