Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3125826 | 0.93 | KDM4E (0.35) | MEN1KMT2ADRD1DRD4DRD5 | |
| SCHEMBL3246677 | 0.88 | ALDH1A1 (0.33) | KMT2ADRD1DRD4DRD5KDM4E | |
| SCHEMBL3240661 | 0.81 | ALDH1A1 (0.35) | DRD1DRD4DRD5KDM4ENPC1 | |
| SCHEMBL826085 | 0.78 | NPC1 (0.54) | MEN1KMT2ADRD1DRD4DRD5 | |
| SCHEMBL3121502 | 0.78 | NPC1 (0.42) | MEN1KMT2AHTTKDM4ENPC1 | |
| SCHEMBL2183432 | 0.77 | KDM4E (0.56) | KDM4EALDH1A1USP2SMN1; SMN2POLB | |
| SCHEMBL11088044 | 0.75 | MEN1 (0.41) | MEN1KMT2AHTTKDM4ENPC1 | |
| SCHEMBL3119172 | 0.75 | NPC1 (0.41) | MEN1KMT2AHTTKDM4ENPC1 | |
| SCHEMBL3119026 | 0.73 | GAA (0.55) | KDM4ENPC1RAB9AALDH1A1USP2 | |
| SCHEMBL3130513 | 0.72 | USP2 (0.56) | KDM4ENPC1RAB9AUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | disclosed |