Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3129786 | 0.84 | TDP2 (0.33) | NPC1PKMALDH1A1TP53 | |
| SCHEMBL3119167 | 0.81 | NPSR1 (0.41) | MEN1KMT2ANPSR1NPC1ALDH1A1 | |
| SCHEMBL3124832 | 0.78 | GRM5 (0.35) | MEN1KMT2AALDH1A1 | |
| SCHEMBL826084 | 0.75 | KCNA5 (0.39) | MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL3130509 | 0.73 | ALDH1A1 (0.44) | MEN1KMT2ANPSR1NPC1ALDH1A1 | |
| SCHEMBL3126463 | 0.72 | — | — | |
| SCHEMBL3124922 | 0.71 | — | — | |
| SCHEMBL3129790 | 0.70 | MEN1 (0.35) | MEN1KMT2ANPC1ALDH1A1HTT | |
| SCHEMBL3125826 | 0.69 | KDM4E (0.35) | MEN1KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL3119020 | 0.68 | ALDH1A1 (0.60) | KMT2AALDH1A1HTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | disclosed |