Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD5 | P21918 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240661 | 0.92 | ALDH1A1 (0.35) | ALDH1A1TDP1CYP2D6CYP2C19KDM4E | |
| SCHEMBL3129790 | 0.88 | MEN1 (0.35) | ALDH1A1CYP2D6KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL3125826 | 0.81 | KDM4E (0.35) | ALDH1A1TDP1CYP2D6KDM4ESMN1; SMN2 | |
| SCHEMBL956747 | 0.78 | LTA4H (0.51) | TDP1CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL2180083 | 0.76 | TSHR (0.53) | TDP1KDM4ESMN1; SMN2DRD1DRD4 | |
| SCHEMBL8623642 | 0.76 | ALDH1A1 (0.55) | ALDH1A1CYP2D6CYP2C19KDM4ESMN1; SMN2 | |
| SCHEMBL6238419 | 0.75 | JAK2 (0.33) | ALDH1A1TDP1KDM4ESMN1; SMN2 | |
| SCHEMBL3583393 | 0.75 | HRH3 (0.54) | ALDH1A1CYP2D6CYP2C19KDM4ESMN1; SMN2 | |
| SCHEMBL11555236 | 0.75 | — | — | |
| SCHEMBL3960266 | 0.73 | ALDH1A1 (0.37) | ALDH1A1TDP1CYP2D6CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | disclosed |