SCHEMBL31298

SCHEMBL31298

Nc1nc2ccc(O)cc2s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 1.00
GAA P10253 1/20 1.00
L3MBTL1 Q9Y468 1/20 1.00
PIK3CA P42336 3/20 0.68
PIK3CD O00329 3/20 0.68
PIK3CG P48736 3/20 0.68
PIK3CB P42338 2/20 0.68
RAB9A P51151 3/20 0.61
MAPT P10636 1/20 0.61
AXL P30530 1/20 0.61
GFER P55789 1/20 0.61
APP P05067 2/20 0.60
CA12 O43570 1/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
CA4 P22748 1/20 0.57
CA6 P23280 1/20 0.57
CA5A P35218 1/20 0.57
CA9 Q16790 1/20 0.57
CA14 Q9ULX7 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11729261 0.98 HTT (0.96) HTTGAAL3MBTL1PIK3CAPIK3CD
SCHEMBL3306309 0.85 PIK3CA (0.74) HTTGAAL3MBTL1PIK3CAPIK3CD
SCHEMBL72699 0.84 GAA (0.72) HTTGAAL3MBTL1PIK3CAPIK3CD
SCHEMBL20855136 0.80 HTT (0.65) HTTGAAL3MBTL1PIK3CAPIK3CD
SCHEMBL29646253 0.79 PIK3CA (0.82) HTTGAAL3MBTL1PIK3CAPIK3CD
SCHEMBL5532470 0.79 PIK3CA (0.82) HTTGAAL3MBTL1PIK3CAPIK3CD
SCHEMBL334946 0.79 RAB9A (0.66) HTTGAAL3MBTL1PIK3CAPIK3CD
SCHEMBL2217147 0.79 HTT (0.66) HTTGAAL3MBTL1MAPTAPP
SCHEMBL1360479 0.78 HTT (0.63) HTTGAAL3MBTL1MAPTAPP
Hydrochloric Acid SCHEMBL3851081 0.78 RAB9A (0.63) HTTGAAL3MBTL1PIK3CAPIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 428 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3494396-B1 CHEMILUMINESCENT AND FLUORESCENT SUBSTRATE PADS AND USES THEREOF PIERCE BIOTECHNOLOGY INC (US) 2025-06-11 EP claimed
CN-119274994-A Preparation process of nickel cobaltate carbon aerogel electrode material 哈尔滨师范大学 2025-01-07 CN claimed
CN-113637158-B High heat-resistant liquid crystal polyester amide film and preparation method thereof 宁波聚嘉新材料科技有限公司 2023-05-19 CN claimed
CN-113637158-A High-heat-resistance liquid crystal polyester amide film and preparation method thereof 宁波聚嘉新材料科技有限公司 2021-11-12 CN claimed
US-10722882-B2 Chemiluminescent and fluorescent substrate pads and uses thereof PIERCE BIOTECHNOLOGY, INC. (US) 2020-07-28 US claimed
CN-110872307-B Thiazole medicine molecule used in hospital and gynecology and preparation method and application thereof 河南科技大学第一附属医院 2020-07-10 CN claimed
CN-110872307-A Thiazole medicine molecule used in hospital and gynecology and preparation method and application thereof 河南科技大学第一附属医院 2020-03-10 CN claimed
CN-110713496-A Thiazole medicine molecule used in hospital and gynecology and preparation method and application thereof 河南科技大学第一附属医院 2020-01-21 CN claimed
CN-110172068-A Benzothiazole compound with anti-tumor activity and its preparation method and application 河南龙湖生物技术有限公司 2019-08-27 CN claimed
EP-3494396-A1 CHEMILUMINESCENT AND FLUORESCENT SUBSTRATE PADS AND USES THEREOF Pierce Biotechnology, Inc. (US) 2019-06-12 EP claimed
EP-2496584-A1 PROCESS FOR THE PREPARATION OF IMIDAZO[2,1-B][1,3]BENZOTHIAZOLE DERIVATIVES Ambit Biosciences Corp. (US) 2012-09-12 EP claimed
CN-102639539-A Process for the preparation of imidazo [2,1-b ] [1,3] benzothiazole derivatives AMBIT BIOSCIENCES CORP 2012-08-15 CN claimed
WO-2011056939-A1 PROCESS FOR THE PREPARATION OF IMIDAZO[2,1-B][1,3]BENZOTHIAZOLE DERIVATIVES AMBIT BIOSCIENCES CORP. (US) 2011-05-12 WO claimed
WO-2006076034-A2 STABILIZED TWO COMPONENT SYSTEM FOR CHEMILUMIESCENT ASSAY IN IMMUNODIAGNOSTICS BHANU, KALRA (US) 2006-07-20 WO claimed
EP-1254252-A4 NOVEL STABILIZED FORMULATIONS FOR CHEMILUMINESCENT ASSAYS GIRI BRIJ P (US) 2006-06-07 EP claimed
US-20050272108-A1 Stabilized two component system for chemiluminescent assay in immunodiagnostics KALRA BHANU 2005-12-08 US claimed
US-6602679-B2 Substrate of an oxidant, stabilizer and buffer with an extended shelf life is useful with enzyme based probes; detecting DNA fragments in DNA sequencing GIRI BRIJ (US) 2003-08-05 US claimed
US-20010046688-A1 Novel stabilized formulations for chemiluminescent assays GIRI BRIJ PAL (US) 2001-11-29 US claimed
WO-2001055446-A1 NOVEL STABILIZED FORMULATIONS FOR CHEMILUMINESCENT ASSAYS GIRI BRIJ PAL (US) 2001-08-02 WO claimed
US-3932435-A Preparation of N-2-(6-hydroxybenzothiazolyl)-N'-phenyl (or substituted-phenyl) ureas ELI LILLY AND COMPANY (US) 1976-01-13 US claimed