Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | MKNK2 | Q9HBH9 | 6/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.40 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3634104 | 0.81 | MKNK2 (0.40) | CA12CA9MKNK2MKNK1PARP1 | |
| SCHEMBL29620435 | 0.81 | MKNK2 (0.40) | CA12CA9MKNK2MKNK1PARP1 | |
| SCHEMBL31297991 | 0.78 | KMT2A (0.44) | MKNK2MKNK1 | |
| SCHEMBL2016705 | 0.76 | CA12 (0.56) | CA12CA9MKNK2MKNK1PARP1 | |
| SCHEMBL31297999 | 0.75 | MKNK2 (0.40) | MKNK2MKNK1GABRG2GABRB3GABRA5 | |
| SCHEMBL24061489 | 0.71 | CA12 (0.42) | CA12CA9MKNK2MKNK1GABRG2 | |
| SCHEMBL22891154 | 0.70 | GABRG2 (0.52) | GABRG2GABRB3GABRA5CLK4DYRK1B | |
| SCHEMBL3918073 | 0.70 | CA12 (0.83) | CA12CA9PARP1TYRO3NTRK2 | |
| SCHEMBL1185539 | 0.70 | KDR (0.56) | GABRG2GABRB3GABRA5 | |
| SCHEMBL14896 | 0.69 | CA12 (1.00) | CA12CA9PARP1TYRO3NTRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250043353-A1 | BIOMARKERS OF RESPONSE TO SELECTIVE INHIBITORS OF AURORA A KINASE | MILLENNIUM PHARM INC (US) | 2025-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250043353-A1 | BIOMARKERS OF RESPONSE TO SELECTIVE INHIBITORS OF AURORA A KINASE | WNT1, XPOT, CTNNBL1 | CA12 3668/4885CA9 4289/4885MKNK2 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.