Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.39 |
| ▸ | SUV39H2 | Q9H5I1 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31298248 | 0.87 | SUV39H2 (0.38) | RAB9ANPC1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL31298263 | 0.87 | ALDH1A1 (0.39) | RAB9ANPC1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL31298258 | 0.85 | NPC1 (0.42) | RAB9ANPC1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL31190882 | 0.83 | ALPL (0.40) | RAB9ANPC1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL31091845 | 0.82 | SUV39H2 (0.45) | RAB9ANPC1MAPTALDH1A1ALDH1A3 | |
| SCHEMBL31298296 | 0.81 | NPC1 (0.38) | RAB9ANPC1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL31298233 | 0.80 | PDK2 (0.46) | RAB9ANPC1MAPTALDH1A1ALDH1A3 | |
| SCHEMBL31298353 | 0.79 | SUV39H2 (0.43) | RAB9ANPC1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL31091930 | 0.79 | SUV39H2 (0.43) | RAB9ANPC1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL31298326 | 0.77 | ALDH1A1 (0.41) | RAB9ANPC1ALDH1A1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4698530-A1 | NK3 MODULATORS AND USES THEREOF | Kallyope, Inc. (US) | 2026-02-25 | — | — | EP | disclosed |
| US-20250263410-A1 | NK3 MODULATORS AND USES THEREOF | KALLYOPE, INC. | 2025-08-21 | — | — | US | disclosed |
| US-12281114-B2 | NK3 modulators and uses thereof | KALLYOPE, INC. (US) | 2025-04-22 | — | — | US | disclosed |
| WO-2024220539-A1 | NK3 MODULATORS AND USES THEREOF | KALLYOPE, INC. (US) | 2024-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250263410-A1 | NK3 MODULATORS AND USES THEREOF | TAC3, TACR3, TACR2 | RAB9A 2411/4885NPC1 959/4885MAPT 4383/4885 |
| US-12281114-B2 | NK3 modulators and uses thereof | TAC3, TACR3, TACR2 | RAB9A 2411/4885NPC1 959/4885MAPT 4383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.