Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | LGMN | Q99538 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13456026 | 0.98 | LMNA (0.58) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9093746 | 0.85 | LMNA (0.71) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL31299594 | 0.79 | ALDH1A1 (0.56) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL574470 | 0.79 | LMNA (0.58) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3949359 | 0.79 | LMNA (0.58) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2175616 | 0.78 | LMNA (0.62) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL21450824 | 0.78 | ALDH1A1 (0.54) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL20908718 | 0.76 | ALDH1A1 (0.58) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL28815529 | 0.76 | LMNA (0.67) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9092806 | 0.76 | LMNA (0.60) | LMNAMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118974021-A | Preparation method of thiobenzimidazole derivative and novel intermediate for same | 高丽大学校产学协力团 | 2024-11-15 | — | — | CN | disclosed |