Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 17/20 | 0.49 |
| ▸ | THRA | P10827 | 16/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25768629 | 1.00 | THRB (0.49) | THRBTHRACYP2C8CYP2C9BCAT1 | |
| SCHEMBL31301036 | 0.92 | THRB (0.40) | THRBTHRACYP2C8CYP2C9PDE10A | |
| SCHEMBL25768628 | 0.89 | THRB (0.53) | THRBTHRACYP2C8CYP2C9 | |
| SCHEMBL30460687 | 0.89 | THRB (0.53) | THRBTHRACYP2C8CYP2C9 | |
| SCHEMBL25769192 | 0.87 | THRB (0.47) | THRBTHRACYP2C8CYP2C9PDE10A | |
| SCHEMBL25291901 | 0.86 | THRB (0.49) | THRBTHRACYP2C8CYP2C9BCAT1 | |
| SCHEMBL30460702 | 0.86 | THRB (0.49) | THRBTHRACYP2C8CYP2C9BCAT1 | |
| SCHEMBL23042578 | 0.84 | THRA (0.54) | THRBTHRACYP2C8CYP2C9 | |
| SCHEMBL31301034 | 0.84 | THRB (0.49) | THRBTHRACYP2C8CYP2C9BCAT1 | |
| SCHEMBL25768563 | 0.84 | THRB (0.49) | THRBTHRACYP2C8CYP2C9BCAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4458820-A1 | CLASS OF QUINOLINE COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2024-11-06 | — | — | EP | claimed |
| EP-4458820-A1 | CLASS OF QUINOLINE COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2024-11-06 | — | — | EP | disclosed |