Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.54 |
| ▸ | CHRNA5 | P30532 | 3/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
| ▸ | F3 | P13726 | 1/20 | 0.45 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.45 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24712427 | 0.82 | HPGD (0.51) | NPC1RAB9AABCG2MAPT | |
| SCHEMBL25170232 | 0.78 | NPC1 (0.48) | CHRNB2CHRNA5CHRNA4NPC1RAB9A | |
| SCHEMBL15597193 | 0.72 | CHRNB2 (0.61) | CHRNB2CHRNA5CHRNA4NPC1RAB9A | |
| SCHEMBL31301189 | 0.71 | FAAH (0.56) | RAB9ACCNA2CDK2CCNA1MKNK2 | |
| SCHEMBL30398916 | 0.70 | ESRRA (0.46) | F7F3SARM1SIRT2SIRT6 | |
| Fumaric Acid SCHEMBL2038382 | 0.70 | CHRNB2 (0.77) | CHRNB2CHRNA5CHRNA4NPC1RAB9A | |
| Fumaric Acid SCHEMBL2038380 | 0.70 | CHRNB2 (0.77) | CHRNB2CHRNA5CHRNA4NPC1RAB9A | |
| SCHEMBL28428606 | 0.69 | CHRNB2 (0.56) | CHRNB2CHRNA5CHRNA4NPC1RAB9A | |
| SCHEMBL3752704 | 0.69 | CHRNB2 (0.73) | CHRNB2CHRNA5CHRNA4NPC1RAB9A | |
| SCHEMBL2211336 | 0.68 | HPGD (0.53) | NPC1RAB9AABCG2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250002487-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2025-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250002487-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | CGAS, TDP1, CYP11B2 | CHRNB2 2274/4885CHRNA5 2983/4885CHRNA4 3362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.