SCHEMBL31301307

SCHEMBL31301307

CN(C(=O)c1cncc(-c2ccc(C3CCC3)cc2)n1)c1ccc(Cl)cc1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 4/20 0.46
SCN10A Q9Y5Y9 6/20 0.43
SCN2A Q99250 5/20 0.43
GPBAR1 Q8TDU6 3/20 0.38
PROKR1 Q8TCW9 3/20 0.37
PIK3CD O00329 1/20 0.36
PIK3CB P42338 1/20 0.36
PI4KA P42356 1/20 0.36
PIK3CG P48736 1/20 0.36
PIK3C3 Q8NEB9 1/20 0.36
HSD17B1 P14061 1/20 0.36
HSD17B2 P37059 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31301497 0.98 DGAT1 (0.46) DGAT1SCN10ASCN2AGPBAR1PROKR1
SCHEMBL31301409 0.97 DGAT1 (0.45) DGAT1SCN10ASCN2AGPBAR1PROKR1
SCHEMBL34461742 0.97 DGAT1 (0.45) DGAT1SCN10ASCN2AGPBAR1PROKR1
SCHEMBL31301435 0.88 SCN10A (0.53) SCN10ASCN2AGPBAR1PIK3CDPIK3CB
SCHEMBL31301480 0.83 SCN10A (0.55) SCN10ASCN2AGPBAR1PIK3CDPIK3CB
SCHEMBL31301346 0.83 SCN10A (0.55) SCN10ASCN2AGPBAR1PIK3CDPIK3CB
SCHEMBL31301446 0.82 DGAT1 (0.49) DGAT1GPBAR1
SCHEMBL31301588 0.81 SCN10A (0.47) SCN10ASCN2AGPBAR1PIK3CDPIK3CB
SCHEMBL31301415 0.80 SCN10A (0.52) SCN10ASCN2AGPBAR1PIK3CDPIK3CB
SCHEMBL31301324 0.79 SCN10A (0.46) SCN10ASCN2AGPBAR1PIK3CDPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727549-A2 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS University of Georgia Research Foundation, Inc. (US) 2026-04-22 EP disclosed
US-20260097046-A1 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS UNIV GEORGIA (US) 2026-04-09 US disclosed
WO-2024258900-A2 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2024-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097046-A1 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS SUB1, PFN1, HCCS DGAT1 1115/4885SCN10A 3171/4885SCN2A 2686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.