SCHEMBL31301324

SCHEMBL31301324

CN(C(=O)c1cncc(-c2ccc(C(F)F)cc2)n1)c1ccc(Cl)cc1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SCN10A Q9Y5Y9 6/20 0.46
SCN2A Q99250 4/20 0.46
GPBAR1 Q8TDU6 5/20 0.40
PIK3CD O00329 1/20 0.38
PIK3CB P42338 1/20 0.38
PI4KA P42356 1/20 0.38
PIK3CG P48736 1/20 0.38
PIK3C3 Q8NEB9 1/20 0.38
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
GRM1 Q13255 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
CHEK2 O96017 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31301588 0.91 SCN10A (0.47) SCN10ASCN2AGPBAR1PIK3CDPIK3CB
SCHEMBL31301435 0.91 SCN10A (0.53) SCN10ASCN2AGPBAR1PIK3CDPIK3CB
SCHEMBL31301346 0.86 SCN10A (0.55) SCN10ASCN2AGPBAR1PIK3CDPIK3CB
SCHEMBL31301480 0.86 SCN10A (0.55) SCN10ASCN2AGPBAR1PIK3CDPIK3CB
SCHEMBL31301275 0.86 SCN10A (0.46) SCN10ASCN2AGPBAR1PIK3CDPIK3CB
SCHEMBL31301360 0.84 GPBAR1 (0.53) SCN10ASCN2AGPBAR1PIK3CDPIK3CB
SCHEMBL31301415 0.83 SCN10A (0.52) SCN10ASCN2AGPBAR1PIK3CDPIK3CB
SCHEMBL31301261 0.81 SCN10A (0.55) SCN10ASCN2AGPBAR1MEN1KMT2A
SCHEMBL31301342 0.80 MEN1 (0.43) SCN10ASCN2AGPBAR1PIK3CDPIK3CB
SCHEMBL34461781 0.79 HSD17B1 (0.46) SCN10ASCN2AGPBAR1GRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727549-A2 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS University of Georgia Research Foundation, Inc. (US) 2026-04-22 EP disclosed
US-20260097046-A1 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS UNIV GEORGIA (US) 2026-04-09 US disclosed
WO-2024258900-A2 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2024-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097046-A1 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS SUB1, PFN1, HCCS SCN10A 3171/4885SCN2A 2686/4885GPBAR1 803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.