SCHEMBL31301347

SCHEMBL31301347

O=C(Nc1ccc(Cl)cc1)c1cncc(-c2ccc(OC(F)(F)F)cc2)n1

nearest known ligand 0.78

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 6/20 0.78
SCN10A Q9Y5Y9 9/20 0.73
SCN2A Q99250 7/20 0.69
NPC1 O15118 1/20 0.59
RAB9A P51151 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
HTT P42858 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16714112 0.87 ABL1 (1.00) ABL1SCN10ASCN2ANPC1RAB9A
SCHEMBL31301529 0.85 SCN10A (0.63) ABL1SCN10ASCN2AMEN1KMT2A
SCHEMBL15390862 0.83 ABL1 (0.69) ABL1SCN10ASCN2ANPC1RAB9A
SCHEMBL31301428 0.81 SCN10A (0.63) ABL1SCN10ASCN2AMEN1KMT2A
SCHEMBL24994330 0.79 SCN10A (0.66) ABL1SCN10ASCN2ANPC1RAB9A
SCHEMBL31301261 0.79 SCN10A (0.55) ABL1SCN10ASCN2AMEN1KMT2A
SCHEMBL31301547 0.79 SCN10A (0.62) ABL1SCN10ASCN2ANPC1RAB9A
SCHEMBL27996626 0.78 SCN10A (0.61) ABL1SCN10ASCN2A
SCHEMBL31301422 0.77 SCN10A (0.52) ABL1SCN10ASCN2A
SCHEMBL31301271 0.77 SCN10A (0.52) ABL1SCN10ASCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727549-A2 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS University of Georgia Research Foundation, Inc. (US) 2026-04-22 EP disclosed
US-20260097046-A1 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS UNIV GEORGIA (US) 2026-04-09 US disclosed
WO-2024258900-A2 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2024-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097046-A1 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS SUB1, PFN1, HCCS ABL1 524/4885SCN10A 3171/4885SCN2A 2686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.