Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 6/20 | 0.62 |
| ▸ | ABL1 | P00519 | 2/20 | 0.59 |
| ▸ | SCN2A | Q99250 | 4/20 | 0.58 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.46 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27996626 | 0.87 | SCN10A (0.61) | SCN10AABL1SCN2ASCN9AADORA3 | |
| SCHEMBL24994330 | 0.86 | SCN10A (0.66) | SCN10AABL1SCN2ACHEK1SCN9A | |
| SCHEMBL28446016 | 0.81 | SUCNR1 (0.62) | SCN10AABL1SCN2ADHODHSCN9A | |
| SCHEMBL31301356 | 0.81 | PARP1 (0.44) | SCN10ACHEK1SCN9AADORA3 | |
| SCHEMBL24499968 | 0.81 | CHEK1 (0.73) | SCN10ASCN2ACHEK1NPC1RAB9A | |
| SCHEMBL21682670 | 0.79 | SCN10A (0.50) | SCN10AABL1SCN2ACHEK1BRAF | |
| SCHEMBL31301347 | 0.79 | ABL1 (0.78) | SCN10AABL1SCN2ANPC1RAB9A | |
| SCHEMBL4820848 | 0.79 | NPC1 (0.46) | SCN10ASCN2ACHEK1DHODHSCN9A | |
| SCHEMBL21001359 | 0.77 | ADORA3 (0.61) | SCN10ADHODHSCN9AADORA3AURKA | |
| SCHEMBL31142985 | 0.77 | CHEK1 (0.59) | SCN10ASCN2ACHEK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727549-A2 | PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS | University of Georgia Research Foundation, Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| US-20260097046-A1 | PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS | UNIV GEORGIA (US) | 2026-04-09 | — | — | US | disclosed |
| WO-2024258900-A2 | PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2024-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260097046-A1 | PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS | SUB1, PFN1, HCCS | SCN10A 3171/4885ABL1 524/4885SCN2A 2686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.