Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 6/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | POLQ | O75417 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31301358 | 0.90 | HSD17B1 (0.49) | TP53MAPTHSD17B1HSD17B2SMN1; SMN2 | |
| SCHEMBL31301411 | 0.87 | POLB (0.45) | TP53MAPTHSD17B1HSD17B2SMN1; SMN2 | |
| SCHEMBL31301355 | 0.86 | ALDH1A1 (0.40) | TP53MAPTHSD17B1HSD17B2SMN1; SMN2 | |
| SCHEMBL31301475 | 0.86 | TP53 (0.38) | TP53MAPTSMN1; SMN2NOTUM | |
| SCHEMBL31301339 | 0.85 | HSD17B2 (0.47) | TP53MAPTHSD17B1HSD17B2SMN1; SMN2 | |
| SCHEMBL31301289 | 0.85 | HSD17B1 (0.44) | TP53MAPTHSD17B1HSD17B2SMN1; SMN2 | |
| SCHEMBL31301267 | 0.81 | GPBAR1 (0.43) | MAPTSMN1; SMN2KDM4EPOLBNOTUM | |
| SCHEMBL31301349 | 0.81 | GPBAR1 (0.43) | MAPTSMN1; SMN2KDM4EPOLBNOTUM | |
| SCHEMBL31301466 | 0.79 | MAPT (0.49) | TP53MAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL31301351 | 0.77 | MAPT (0.43) | TP53MAPTHSD17B1HSD17B2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727549-A2 | PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS | University of Georgia Research Foundation, Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| US-20260097046-A1 | PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS | UNIV GEORGIA (US) | 2026-04-09 | — | — | US | disclosed |
| WO-2024258900-A2 | PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2024-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260097046-A1 | PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS | SUB1, PFN1, HCCS | TP53 4222/4885MAPT 4575/4885HSD17B1 1543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.