SCHEMBL31301418

SCHEMBL31301418

O=S(=O)=C1CC=Cc2c1ccc1ccccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.35
HPGD P15428 3/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2C19 P33261 2/20 0.35
HIF1A Q16665 2/20 0.35
MEN1 O00255 2/20 0.35
LMNA P02545 2/20 0.35
KMT2A Q03164 2/20 0.35
USP2 O75604 1/20 0.35
TP53 P04637 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
ALOX12 P18054 1/20 0.35
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 2/20 0.34
HSD17B10 Q99714 2/20 0.34
CYP2A6 P11509 1/20 0.34
TSHR P16473 1/20 0.34
DNMT1 P26358 1/20 0.34
CA12 O43570 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3258162 0.78 ALDH1A1 (0.41) ALDH1A1HPGDCYP1A2CYP2C19HIF1A
SCHEMBL29563614 0.78 ALDH1A1 (0.41) ALDH1A1HPGDCYP1A2CYP2C19HIF1A
SCHEMBL31186571 0.75 ALDH1A1 (0.38) ALDH1A1HPGDCYP1A2CYP2C19HIF1A
SCHEMBL7526281 0.75 ALDH1A1 (0.38) ALDH1A1HPGDCYP1A2CYP2C19HIF1A
SCHEMBL3726944 0.73 MAPT (0.33) ALDH1A1KMT2AMAPK1L3MBTL1KDM4E
SCHEMBL29181691 0.71 ALDH1A1 (0.49) ALDH1A1HPGDCYP1A2CYP2C19HIF1A
SCHEMBL29442976 0.70 ALDH1A1 (0.44) ALDH1A1HPGDCYP1A2CYP2C19HIF1A
SCHEMBL4623560 0.70 ALDH1A1 (0.44) ALDH1A1HPGDCYP1A2CYP2C19HIF1A
SCHEMBL6035256 0.68 ALDH1A1 (0.36) ALDH1A1HPGDCYP1A2CYP2C19MEN1
Lithium SCHEMBL29767624 0.68 ALDH1A1 (0.42) ALDH1A1HPGDCYP1A2CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118978463-A Synthesis method of 9-aryl-10-sulfoxide phenanthrene compound 淮北师范大学 2024-11-19 CN disclosed