SCHEMBL7526281

SCHEMBL7526281

C=C1CC=Cc2c1ccc1ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
CYP2A6 P11509 3/20 0.38
HSD17B10 Q99714 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
TSHR P16473 2/20 0.38
HPRT1 P00492 1/20 0.35
CYP1A2 P05177 3/20 0.34
HIF1A Q16665 2/20 0.34
HPGD P15428 2/20 0.34
CYP2C19 P33261 2/20 0.34
MEN1 O00255 1/20 0.34
USP2 O75604 1/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
ALOX12 P18054 1/20 0.34
MAPK1 P28482 1/20 0.34
KMT2A Q03164 1/20 0.34
DNMT1 P26358 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3258162 0.79 ALDH1A1 (0.41) ALDH1A1CYP2A6HSD17B10TDP1TSHR
SCHEMBL31186571 0.79 ALDH1A1 (0.38) ALDH1A1CYP2A6HSD17B10TDP1TSHR
SCHEMBL29563614 0.79 ALDH1A1 (0.41) ALDH1A1CYP2A6HSD17B10TDP1TSHR
SCHEMBL31301418 0.75 ALDH1A1 (0.35) ALDH1A1CYP2A6HSD17B10TDP1TSHR
SCHEMBL10446467 0.75 ALDH1A1 (0.34) ALDH1A1CYP2A6HSD17B10TDP1TSHR
SCHEMBL4623560 0.73 ALDH1A1 (0.44) ALDH1A1CYP2A6HSD17B10TDP1TSHR
SCHEMBL29442976 0.73 ALDH1A1 (0.44) ALDH1A1CYP2A6HSD17B10TDP1TSHR
Lithium SCHEMBL29767624 0.72 ALDH1A1 (0.42) ALDH1A1CYP2A6HSD17B10TDP1TSHR
SCHEMBL29636355 0.71 CES1 (0.46) ALDH1A1CYP2A6HSD17B10TDP1TSHR
SCHEMBL2990894 0.71 HSD17B10 (0.40) ALDH1A1CYP2A6HSD17B10TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0253529-B1 FLUORINATED POLYCYCLIC COMPOUNDS ISC CHEMICALS LIMITED (GB) 1990-09-26 EP claimed
EP-0253529-A1 Fluorinated polycyclic compounds ISC CHEMICALS LIMITED (GB) 1988-01-20 EP claimed
CN-116284136-A Small-space barrier, high-boiling point, strong-coordination and large-volume organic phosphine ligand and preparation method and application thereof 深圳市硕果科技有限公司 2023-06-23 CN disclosed
EP-1200491-A1 ETHYLENE AND/OR ALPHA-OLEFIN/VINYL OR VINYLIDENE AROMATIC INTERPOLYMER COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 2002-05-02 EP disclosed
EP-0773238-B1 Method for controlling the melting points and molecular weights of syndiotactic polyolefins using metallocene catalyst systems FINA TECHNOLOGY (US) 2002-03-20 EP disclosed
EP-0773239-B1 Method for controlling the melting points and molecular weights of syndiotactic polyolefins using metallocene catalyst systems FINA TECHNOLOGY (US) 2001-12-05 EP disclosed
WO-2000078831-A1 ETHYLENE AND/OR ALPHA-OLEFIN/VINYL OR VINYLIDENE AROMATIC INTERPOLYMER COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 2000-12-28 WO disclosed
EP-0577581-B1 Method for controlling the melting points and molecular weights of syndiotactic polyolefins using metallocene catalyst systems FINA TECHNOLOGY (US) 2000-07-05 EP disclosed
US-5710222-A CATALYTIC POLYMERIZATION OF PROPYLENE WITH METALLOCENE COMPOUND WITH GROUP IVB METAL AND EXTRATION FINA TECHNOLOGY, INC. (US) 1998-01-20 US disclosed
US-5688735-A COORDINATION CATALYST FINA TECHNOLOGY, INC. (US) 1997-11-18 US disclosed
EP-0773239-A2 Method for controlling the melting points and molecular weights of syndiotactic polyolefins using metallocene catalyst systems FINA TECHNOLOGY, INC. (US) 1997-05-14 EP disclosed
EP-0773238-A2 Method for controlling the melting points and molecular weights of syndiotactic polyolefins using metallocene catalyst systems FINA TECHNOLOGY, INC. (US) 1997-05-14 EP disclosed
EP-0577581-A2 Method for controlling the melting points and molecular weights of syndiotactic polyolefins using metallocene catalyst systems FINA TECHNOLOGY, INC. (US) 1994-01-05 EP disclosed
EP-0253529-B1 FLUORINATED POLYCYCLIC COMPOUNDS ISC CHEMICALS LIMITED (GB) 1990-09-26 EP disclosed
US-4895990-A HIGH TEMPERATURE VAPOR SOLDERING FLUID, HEAT TRANSFER I.S.C. CHEMICALS LIMITED (GB) 1990-01-23 US disclosed
EP-0253529-A1 Fluorinated polycyclic compounds ISC CHEMICALS LIMITED (GB) 1988-01-20 EP disclosed
US-4075157-A PRODUCTION OF NON-CARCINOGENIC CARBON BLACK PHILLIPS PETROLEUM COMPANY (US) 1978-02-21 US disclosed
US-4075160-A NON-CARCINOGENIC CARBON BLACK PHILLIPS PETROLEUM COMPANY (US) 1978-02-21 US disclosed