SCHEMBL31301533

SCHEMBL31301533

CN(C(=O)c1cncc(-c2ccc(C(F)(F)F)cc2)n1)c1ccc(Cl)nn1

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SCN10A Q9Y5Y9 8/20 0.37
CASP1 P29466 1/20 0.37
SCN2A Q99250 6/20 0.36
GPBAR1 Q8TDU6 2/20 0.35
SCN9A Q15858 2/20 0.35
JUN P05412 1/20 0.35
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
PIM1 P11309 2/20 0.34
PIM3 Q86V86 2/20 0.34
ADORA3 P0DMS8 1/20 0.34
PARP1 P09874 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31301305 0.88 SCN10A (0.37) SCN10ASCN2AGPBAR1SCN9APIM1
SCHEMBL31301449 0.85 SCN10A (0.41) SCN10ACASP1SCN2AGPBAR1SCN9A
SCHEMBL31301526 0.83 GPBAR1 (0.41) SCN10ASCN2AGPBAR1SCN9APARP1
SCHEMBL31301329 0.82 SCN10A (0.39) SCN10ASCN2AGPBAR1SCN9APIM1
SCHEMBL31301360 0.81 GPBAR1 (0.53) SCN10ASCN2AGPBAR1SCN9A
SCHEMBL31301619 0.80 MLYCD (0.46) SCN10ASCN2AGPBAR1SCN9AADORA3
SCHEMBL31301681 0.80 MPL (0.38) SCN10AGPBAR1SCN9APARP1
SCHEMBL31301571 0.80 SCN10A (0.44) SCN10ACASP1SCN2AGPBAR1SCN9A
SCHEMBL31301404 0.78 GPBAR1 (0.39) SCN10ASCN2AGPBAR1SCN9APIM1
SCHEMBL31301363 0.78 GPBAR1 (0.42) SCN10AGPBAR1SCN9AADORA3PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727549-A2 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS University of Georgia Research Foundation, Inc. (US) 2026-04-22 EP disclosed
US-20260097046-A1 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS UNIV GEORGIA (US) 2026-04-09 US disclosed
WO-2024258900-A2 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2024-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097046-A1 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS SUB1, PFN1, HCCS SCN10A 3171/4885CASP1 1021/4885SCN2A 2686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.