Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 5/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 2/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.38 |
| ▸ | POLQ | O75417 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31301568 | 0.92 | GPBAR1 (0.54) | GPBAR1KDM1AHDAC1SCN10AMAP4K4 | |
| SCHEMBL31301417 | 0.82 | MAP4K4 (0.52) | GPBAR1SCN10AMAP4K4SCN2AMEN1 | |
| SCHEMBL31301375 | 0.82 | MLYCD (0.48) | GPBAR1KDM1AHDAC1SCN10AMLYCD | |
| SCHEMBL31301522 | 0.80 | GPBAR1 (0.46) | GPBAR1SCN10ASCN2ALIPEMEN1 | |
| SCHEMBL31301548 | 0.78 | SCN10A (0.54) | GPBAR1HDAC1SCN10AMAP4K4SCN2A | |
| SCHEMBL31301640 | 0.76 | SCN10A (0.65) | KDM1AHDAC1SCN10ASCN2AKCNH2 | |
| SCHEMBL31301503 | 0.76 | SCN10A (0.46) | GPBAR1SCN10AMAP4K4SCN2A | |
| SCHEMBL31301426 | 0.75 | SCN10A (0.47) | GPBAR1SCN10AMAP4K4SCN2A | |
| SCHEMBL31301555 | 0.72 | GPBAR1 (0.54) | GPBAR1SCN10AMAP4K4SCN2A | |
| SCHEMBL13876033 | 0.72 | KDM1A (0.54) | KDM1AHDAC1SCN10AMAP4K4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727549-A2 | PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS | University of Georgia Research Foundation, Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| US-20260097046-A1 | PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS | UNIV GEORGIA (US) | 2026-04-09 | — | — | US | disclosed |
| WO-2024258900-A2 | PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2024-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260097046-A1 | PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS | SUB1, PFN1, HCCS | GPBAR1 803/4885KDM1A 3809/4885HDAC1 1273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.