SCHEMBL31301587

SCHEMBL31301587

Cc1cnc(N(C)C(=O)c2cncc(-c3ccc(C(F)(F)F)cc3)n2)s1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CTSA P10619 2/20 0.38
SCN10A Q9Y5Y9 4/20 0.37
PARP1 P09874 1/20 0.36
ALDH1A1 P00352 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
SCN2A Q99250 3/20 0.35
SCN9A Q15858 1/20 0.35
PPARA Q07869 1/20 0.35
SCD O00767 1/20 0.35
GRM1 Q13255 2/20 0.35
NPC1 O15118 1/20 0.35
GAA P10253 1/20 0.35
HSD17B10 Q99714 3/20 0.35
TSHR P16473 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31301554 0.83 SCN10A (0.37) SCN10APARP1ALDH1A1SCN2ASCN9A
SCHEMBL31301330 0.83 GRM1 (0.39) SCN10APARP1ALDH1A1L3MBTL1SCN9A
SCHEMBL31301619 0.80 MLYCD (0.46) SCN10APARP1SCN2ASCN9A
SCHEMBL31301297 0.80 GPBAR1 (0.40) SCN10APARP1L3MBTL1SCN2ASCN9A
SCHEMBL31301329 0.80 SCN10A (0.39) SCN10APARP1L3MBTL1SCN2ASCN9A
SCHEMBL31301631 0.78 ALDH1A1 (0.36) SCN10APARP1ALDH1A1L3MBTL1SCN2A
SCHEMBL31301363 0.78 GPBAR1 (0.42) SCN10APARP1SCN9AGRM1
SCHEMBL31301441 0.77 SMN1; SMN2 (0.53) SCN10ASCN2ANPC1
SCHEMBL31301681 0.77 MPL (0.38) SCN10APARP1SCN9A
SCHEMBL31301305 0.77 SCN10A (0.37) SCN10APARP1SCN2ASCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727549-A2 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS University of Georgia Research Foundation, Inc. (US) 2026-04-22 EP disclosed
US-20260097046-A1 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS UNIV GEORGIA (US) 2026-04-09 US disclosed
WO-2024258900-A2 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2024-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097046-A1 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS SUB1, PFN1, HCCS CTSA 1165/4885SCN10A 3171/4885PARP1 611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.