Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UNG | P13051 | 1/20 | 0.71 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.69 |
| ▸ | KMO | O15229 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.53 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL758230 | 0.89 | AKR1C3 (0.72) | UNGAKR1C3KMOKDM4ENPC1 | |
| SCHEMBL4100666 | 0.89 | TRIM24 (0.59) | UNGAKR1C3KMOKDM4ETRIM24 | |
| SCHEMBL30449599 | 0.86 | AKR1C3 (0.92) | AKR1C3KMOKDM4ENPC1POLB | |
| SCHEMBL68858 | 0.86 | AKR1C3 (0.92) | AKR1C3KMOKDM4ENPC1POLB | |
| SCHEMBL30307454 | 0.86 | AKR1C3 (0.92) | AKR1C3KMOKDM4ENPC1POLB | |
| SCHEMBL1635565 | 0.84 | AKR1C3 (0.88) | AKR1C3KMOKDM4ENPC1POLB | |
| SCHEMBL30266792 | 0.84 | AKR1C3 (0.88) | AKR1C3KMOKDM4ENPC1POLB | |
| Benzene SCHEMBL17267850 | 0.84 | MAOA (0.58) | UNGPPARGNPC1RAB9ASRC | |
| 3-Formylbenzoic Acid SCHEMBL266698 | 0.84 | UNG (1.00) | UNGKMOKDM4ETRIM24TRIM33 | |
| 3-Formylbenzoic Acid SCHEMBL29514486 | 0.84 | UNG (1.00) | UNGKMOKDM4ETRIM24TRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010002483-A1 | OPTIONALLY CONDENSED DIHYDRO PYRIDINE, DIHYDROPYRIMIDINE AND DIHYDRO PYRANE DERIVATIVES ACTING AS LATE SODIUM CHANNEL BLOCKERS | CV THERAPEUTICS, INC. (US) | 2010-01-07 | — | — | WO | disclosed |