Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.59 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.59 |
| ▸ | UNG | P13051 | 1/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.50 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | KMO | O15229 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | TNKS | O95271 | 1/20 | 0.49 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | ACP1 | P24666 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3130174 | 0.89 | UNG (0.71) | TRIM24TRIM33UNGAKR1C3KDM4E | |
| SCHEMBL11220393 | 0.88 | SRD5A2 (0.58) | UNGSRD5A2AKR1C3PARP10PARP15 | |
| SCHEMBL11222905 | 0.86 | MAOB (0.59) | AKR1C3ALDH1A1SRCMEN1KMT2A | |
| SCHEMBL6856729 | 0.86 | SRC (0.56) | ALDH1A1KDM4ESRCMEN1KMT2A | |
| SCHEMBL11482497 | 0.84 | MAOB (0.61) | AKR1C3ALDH1A1SRCMEN1KMT2A | |
| SCHEMBL29484309 | 0.84 | MAOB (0.61) | AKR1C3ALDH1A1SRCMEN1KMT2A | |
| SCHEMBL2708209 | 0.84 | SRD5A2 (0.71) | SRD5A2AKR1C3PARP10PARP15KDM4E | |
| SCHEMBL98478 | 0.84 | MAOB (0.61) | AKR1C3ALDH1A1SRCMEN1KMT2A | |
| SCHEMBL758230 | 0.84 | AKR1C3 (0.72) | UNGAKR1C3ALDH1A1PARP10PARP15 | |
| SCHEMBL20772350 | 0.83 | ALDH1A1 (0.58) | ALDH1A1PARP10PARP15PARP3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1882684-B1 | PYRROLIDINE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-12-10 | — | — | EP | disclosed |
| US-7585886-B2 | Pyrrolidine derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2009-09-08 | — | — | US | disclosed |
| US-20090062366-A1 | Pyrrolidine derivative or salt thereof | ASTELLAS PHARAMA INC. (JP) | 2009-03-05 | — | — | US | disclosed |
| EP-1882684-A1 | PYRROLIDINE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2008-01-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062366-A1 | Pyrrolidine derivative or salt thereof | CASR, CYP2R1, PTH1R | TRIM24 3620/4885TRIM33 3354/4885UNG 2047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.