Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31304277 | 0.84 | GPR119 (0.47) | GPR119MEN1KMT2A | |
| SCHEMBL5765543 | 0.80 | GPR119 (0.56) | GPR119 | |
| SCHEMBL3506818 | 0.78 | GPR119 (0.46) | GPR119MEN1KMT2A | |
| SCHEMBL28808134 | 0.77 | KDM4E (0.51) | GPR119KDM4EPKM | |
| SCHEMBL14240648 | 0.76 | TRPV3 (0.51) | GPR119KDM4E | |
| SCHEMBL4039291 | 0.75 | GPR119 (0.57) | GPR119 | |
| SCHEMBL3511990 | 0.75 | EED (0.47) | GPR119 | |
| SCHEMBL31304583 | 0.74 | PRMT5 (0.53) | — | |
| SCHEMBL31304569 | 0.74 | PRMT5 (0.53) | — | |
| SCHEMBL4269162 | 0.74 | GPR119 (0.55) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724443-A1 | PYRAZOLO-PYRIMIDINONE COMPOUNDS FOR USE IN METHODS OF INHIBITING WEE1 A KINASE | Acrivon Therapeutics, Inc. (US) | 2026-04-15 | — | — | EP | disclosed |
| WO-2024254490-A1 | PYRAZOLO-PYRIMIDINONE COMPOUNDS FOR USE IN METHODS OF INHIBITING WEE1 A KINASE | ACRIVON THERAPEUTICS, INC. (US) | 2024-12-12 | — | — | WO | disclosed |