Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29130767 | 0.83 | MAPT (0.58) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL12031278 | 0.83 | PDK1 (0.63) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL19175453 | 0.79 | LMNA (0.44) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL4203555 | 0.79 | NPC1 (0.41) | MAPTSMN1; SMN2ALOX5NPC1RAB9A | |
| SCHEMBL19150666 | 0.79 | CYP2C19 (0.43) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL30738210 | 0.79 | CYP2C19 (0.43) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL29534282 | 0.78 | HPGD (0.61) | MAPTSMN1; SMN2NPC1ALDH1A1KMT2A | |
| SCHEMBL14691594 | 0.78 | HPGD (0.61) | MAPTSMN1; SMN2NPC1ALDH1A1KMT2A | |
| SCHEMBL31305103 | 0.78 | P2RX7 (0.39) | ALDH1A1 | |
| SCHEMBL13412121 | 0.77 | CYP2C19 (0.44) | MAPTSMN1; SMN2ALOX5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024238872-A2 | ISOINDOLINONE-GLUTARIMIDE ANTIBODY CONJUGATES, AND USES THEREOF | FIREFLY BIO, INC. (US) | 2024-11-21 | — | — | WO | disclosed |