Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.65 |
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16000906 | 0.88 | ALDH1A1 (0.64) | ALDH1A1MAPTKDM4EMAPK1CYP1A2 | |
| SCHEMBL989117 | 0.85 | ALDH1A1 (0.60) | ALDH1A1MAPTKDM4EMAPK1CYP1A2 | |
| SCHEMBL8065645 | 0.84 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4EMAPK1CYP1A2 | |
| SCHEMBL61187 | 0.84 | POLB (0.71) | ALDH1A1MAPTKDM4ECYP1A2CYP2C9 | |
| SCHEMBL29739620 | 0.84 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4ECYP1A2RAB9A | |
| SCHEMBL29739277 | 0.82 | POLB (0.69) | ALDH1A1MAPTKDM4EMAPK1CYP1A2 | |
| SCHEMBL13593024 | 0.82 | MAPT (0.57) | ALDH1A1MAPTKDM4ECYP1A2POLB | |
| SCHEMBL8603028 | 0.82 | MAPT (0.78) | ALDH1A1MAPTKDM4EMAPK1CYP1A2 | |
| SCHEMBL15374817 | 0.81 | ALDH1A1 (0.60) | ALDH1A1MAPTKDM4EMAPK1CYP1A2 | |
| SCHEMBL8652810 | 0.81 | MAPT (0.76) | ALDH1A1MAPTKDM4EMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024238872-A2 | ISOINDOLINONE-GLUTARIMIDE ANTIBODY CONJUGATES, AND USES THEREOF | FIREFLY BIO, INC. (US) | 2024-11-21 | — | — | WO | disclosed |