Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16000906 | 0.86 | ALDH1A1 (0.64) | ALDH1A1MAPTCYP1A2KDM4EPOLB | |
| SCHEMBL11492965 | 0.85 | ALDH1A1 (0.59) | ALDH1A1MAPTCYP1A2KDM4EMEN1 | |
| SCHEMBL31305228 | 0.84 | ALDH1A1 (0.65) | ALDH1A1MAPTCYP1A2KDM4EPOLB | |
| SCHEMBL989117 | 0.84 | ALDH1A1 (0.60) | ALDH1A1MAPTCYP1A2KDM4EPOLB | |
| SCHEMBL18636419 | 0.82 | POLB (0.45) | ALDH1A1MAPTCYP1A2KDM4EPOLB | |
| SCHEMBL61187 | 0.82 | POLB (0.71) | ALDH1A1MAPTCYP1A2KDM4EPOLB | |
| SCHEMBL29739620 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MAPTCYP1A2KDM4EPOLB | |
| SCHEMBL11127175 | 0.82 | ALDH1A1 (0.56) | ALDH1A1MAPTCYP1A2KDM4EPOLB | |
| SCHEMBL11131058 | 0.82 | POLB (0.63) | ALDH1A1MAPTCYP1A2KDM4EPOLB | |
| SCHEMBL28282044 | 0.82 | RAD51 (0.57) | ALDH1A1MAPTCYP1A2KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143917-A | FROM A DIARYL CARBONATE AND AN AMINE COMPOUND HAVING AT LEAST ONE HYDROGEN ATOM LOCATED AT AN N-POSITION UNDER MODERATE CONDITIONS AT A HIGH REACTION RATE WITH A HIGH SELECTIVITY AND WITH A HIGH YIELD | UBE INDUSTRIES, LTD. (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0902014-A1 | PROCESS FOR PRODUCING ARYL CARBAMATES | UBE INDUSTRIES LIMITED (JP) | 1999-03-17 | — | — | EP | disclosed |