Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 8/20 | 0.46 |
| ▸ | YAP1 | P46937 | 3/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25928450 | 0.89 | PRMT5 (0.47) | PRMT5YAP1GPR119NR4A2MAOB | |
| SCHEMBL29197711 | 0.85 | PRMT5 (0.38) | PRMT5GPR119OPRD1OPRK1 | |
| SCHEMBL24881275 | 0.80 | NR1H2 (0.42) | GPR119 | |
| SCHEMBL8195218 | 0.79 | NAMPT (0.57) | PRMT5YAP1GPR119 | |
| SCHEMBL31510781 | 0.79 | GPR119 (0.47) | GPR119 | |
| SCHEMBL16874689 | 0.78 | PRMT5 (0.50) | PRMT5YAP1GPR119LTA4H | |
| SCHEMBL31700808 | 0.78 | PTPN2 (0.43) | GPR119 | |
| SCHEMBL25936712 | 0.78 | NAMPT (0.50) | PRMT5YAP1GPR119 | |
| SCHEMBL30207514 | 0.77 | GRM5 (0.42) | YAP1GPR119GHSR | |
| SCHEMBL23783422 | 0.77 | GRM5 (0.42) | YAP1GPR119GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431366-A | IRAK4 degradation agent compound and application thereof | 江苏先声药业有限公司 | 2025-02-14 | — | — | CN | disclosed |