Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.39 |
| ▸ | CIT | O14578 | 1/20 | 0.39 |
| ▸ | GAK | O14976 | 1/20 | 0.39 |
| ▸ | PRKX | P51817 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 10/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3129261 | 0.90 | AAK1 (0.39) | AAK1LMNAMEN1MAPTMAPK1 | |
| SCHEMBL3121296 | 0.86 | L3MBTL1 (0.39) | AAK1CITGAKPRKXPRKCQ | |
| SCHEMBL3121033 | 0.86 | ALDH1A1 (0.42) | AAK1PDE4BMEN1MAPTMAPK1 | |
| SCHEMBL3132081 | 0.85 | CIT (0.38) | AAK1CITGAKPRKXPRKCQ | |
| SCHEMBL3121098 | 0.85 | AAK1 (0.40) | AAK1LMNAMEN1MAPK1KMT2A | |
| SCHEMBL3126180 | 0.84 | AAK1 (0.39) | AAK1LMNAMEN1KMT2A | |
| SCHEMBL3132196 | 0.84 | PDE4B (0.49) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3120367 | 0.84 | L3MBTL1 (0.39) | AAK1CITGAKPRKXPRKCQ | |
| SCHEMBL3117583 | 0.84 | MAPT (0.44) | AAK1MEN1MAPTMAPK1KMT2A | |
| SCHEMBL3129614 | 0.81 | PDE4B (0.40) | PDE4BLMNAMEN1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |