Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.81 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 9/20 | 0.71 |
| ▸ | TP53 | P04637 | 5/20 | 0.71 |
| ▸ | GAA | P10253 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | PKM | P14618 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | CLK1 | P49759 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | MC4R | P32245 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5327687 | 1.00 | PAX8 (0.81) | PAX8CREBBPMAPTTP53GAA | |
| SCHEMBL23493756 | 0.94 | PAX8 (0.75) | PAX8CREBBPMAPTTP53GAA | |
| SCHEMBL5332873 | 0.92 | PAX8 (0.85) | PAX8CREBBPMAPTTP53GAA | |
| SCHEMBL403648 | 0.91 | PAX8 (0.68) | PAX8CREBBPMAPTTP53GAA | |
| SCHEMBL5332891 | 0.91 | PAX8 (0.83) | PAX8CREBBPMAPTTP53GAA | |
| SCHEMBL5328005 | 0.91 | PAX8 (0.83) | PAX8CREBBPMAPTTP53GAA | |
| Hydrochloric Acid SCHEMBL15093957 | 0.90 | PAX8 (0.70) | PAX8CREBBPMAPTTP53GAA | |
| SCHEMBL4749734 | 0.90 | PAX8 (0.67) | PAX8CREBBPMAPTTP53GAA | |
| SCHEMBL23494034 | 0.90 | MAPT (0.74) | PAX8MAPTTP53GAALMNA | |
| SCHEMBL5325640 | 0.90 | PAX8 (0.85) | PAX8CREBBPMAPTTP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260115182-A1 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | CHILDRENS MEDICAL CENTER (US) | 2026-04-30 | — | — | US | disclosed |
| US-12171755-B2 | PAPD5 inhibitors and methods of use thereof | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2024-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12171755-B2 | PAPD5 inhibitors and methods of use thereof | PARP15, PAPSS1, PGA5 | PAX8 3073/4885CREBBP 1297/4885MAPT 3447/4885 |
| US-20260115182-A1 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | POT1, TERT, BRCA1 | PAX8 2556/4885CREBBP 610/4885MAPT 2908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.