Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700367 | 0.81 | SMN1; SMN2 (0.47) | EPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL30700371 | 0.81 | ENPP2 (0.43) | GAATDP1CYP2C9TSHRATM | |
| SCHEMBL30700172 | 0.81 | ENPP2 (0.43) | GAATDP1CYP2C9TSHRATM | |
| SCHEMBL25253376 | 0.81 | CACNA1B (0.48) | EPHX2CACNA1BALDH1A1TRPV4SMN1; SMN2 | |
| SCHEMBL30700445 | 0.80 | CACNA1B (0.38) | EPHX2CACNA1BTRPV4CYP2C9CNR2 | |
| SCHEMBL30700102 | 0.79 | GAA (0.43) | GAATDP1CYP2C9ATML3MBTL1 | |
| SCHEMBL30699891 | 0.79 | GAA (0.43) | GAATDP1CYP2C9ATML3MBTL1 | |
| SCHEMBL25327528 | 0.78 | CACNA1B (0.40) | EPHX2CACNA1BTRPV4CYP2C9CNR2 | |
| SCHEMBL25146124 | 0.78 | MGLL (0.43) | EPHX2CACNA1BALDH1A1TRPV4CYP2C9 | |
| SCHEMBL30409323 | 0.78 | MGLL (0.43) | EPHX2CACNA1BALDH1A1TRPV4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119301113-A | Novel heterocyclic carbonyl cyclic compounds as MAGL inhibitors | 豪夫迈·罗氏有限公司 | 2025-01-10 | — | — | CN | claimed |
| CN-119301113-A | Novel heterocyclic carbonyl cyclic compounds as MAGL inhibitors | 豪夫迈·罗氏有限公司 | 2025-01-10 | — | — | CN | disclosed |