Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31308703 | 0.78 | LMNA (0.38) | PDE4APDE4BPDE4CPDE4DMIF | |
| SCHEMBL9296414 | 0.75 | NPSR1 (0.34) | MIFHTTTSHRMAPK10MAPK1 | |
| SCHEMBL14083176 | 0.72 | — | — | |
| SCHEMBL30899554 | 0.72 | — | — | |
| SCHEMBL473005 | 0.72 | — | — | |
| SCHEMBL3956729 | 0.70 | KMT2A (0.41) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL13765461 | 0.68 | L3MBTL1 (0.35) | HTTTSHRHSD17B10KDM4E | |
| SCHEMBL3981656 | 0.67 | CYP1A2 (0.68) | PDE4APDE4BPDE4CPDE4DMIF | |
| SCHEMBL4410328 | 0.66 | PDE4A (0.33) | PDE4APDE4BPDE4CPDE4DMIF | |
| SCHEMBL1237633 | 0.64 | CA1 (0.37) | PDE4APDE4BPDE4CPDE4DMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119301113-A | Novel heterocyclic carbonyl cyclic compounds as MAGL inhibitors | 豪夫迈·罗氏有限公司 | 2025-01-10 | — | — | CN | disclosed |