Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13765305 | 0.72 | NAPRT (0.32) | L3MBTL1ALDH1A1NAPRTHTT | |
| SCHEMBL13765485 | 0.69 | NOS3 (0.32) | HTT | |
| SCHEMBL31308751 | 0.68 | PDE4A (0.40) | KDM4EHSD17B10HTTTSHR | |
| SCHEMBL167456 | 0.67 | NAPRT (0.61) | L3MBTL1KDM4EHSD17B10ALDH1A1NAPRT | |
| SCHEMBL29412876 | 0.67 | NAPRT (0.61) | L3MBTL1KDM4EHSD17B10ALDH1A1NAPRT | |
| SCHEMBL2740726 | 0.67 | TSHR (0.42) | KDM4EHSD17B10ALDH1A1ALOX15HTT | |
| SCHEMBL8993717 | 0.67 | ALDH1A1 (0.53) | L3MBTL1KDM4EHSD17B10ALDH1A1PKM | |
| SCHEMBL12261622 | 0.66 | TNK2 (0.46) | KDM4EALDH1A1NAPRTSCN9A | |
| Hydrochloric Acid SCHEMBL29373852 | 0.66 | NAPRT (0.59) | L3MBTL1KDM4EHSD17B10ALDH1A1NAPRT | |
| SCHEMBL13363938 | 0.65 | KDM4E (0.52) | L3MBTL1KDM4EHSD17B10ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009084621-A1 | PYRIDINE DERIVATIVE SUBSTITUTED WITH HETEROCYCLE AND PHOSPHONOXYMETHYL GROUP AND ANTIFUNGAL AGENT CONTAINING THE SAME | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009081970-A1 | PROCESS FOR PRODUCTION OF HETEROCYCLE-SUBSTITUTED PYRIDINE DERIVATIVE | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |