Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | P2RY1 | P47900 | 5/20 | 0.66 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.66 |
| ▸ | DTYMK | P23919 | 3/20 | 0.58 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.56 |
| ▸ | SRC | P12931 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.56 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.56 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.56 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.55 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.55 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.55 |
| ▸ | LDHA | P00338 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | FBP1 | P09467 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.55 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26667708 | 0.91 | POLB (0.57) | POLBP2RY1ENPP1 | |
| SCHEMBL22875582 | 0.90 | POLB (0.65) | POLBP2RY1ENPP1DTYMKP2RY2 | |
| SCHEMBL16248673 | 0.89 | POLB (0.74) | POLBP2RY1ENPP1DTYMKP2RY2 | |
| SCHEMBL19051966 | 0.89 | POLB (0.74) | POLBP2RY1ENPP1DTYMKP2RY2 | |
| SCHEMBL17972805 | 0.88 | POLB (0.55) | POLBP2RY1ENPP1 | |
| SCHEMBL77641 | 0.88 | POLB (0.81) | POLBP2RY1ENPP1DTYMKP2RY2 | |
| SCHEMBL2508784 | 0.88 | POLB (0.81) | POLBP2RY1ENPP1DTYMKP2RY2 | |
| SCHEMBL31211719 | 0.88 | POLB (0.81) | POLBP2RY1ENPP1DTYMKP2RY2 | |
| SCHEMBL29352481 | 0.88 | POLB (0.81) | POLBP2RY1ENPP1DTYMKP2RY2 | |
| SCHEMBL543475 | 0.88 | POLB (0.81) | POLBP2RY1ENPP1P2RY2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4704829-A2 | SUBSTITUTED BICYCLIC HETEROCYCLE COMPOUNDS, COMPOSITIONS, AND USES THEREOF | Lakewood Amedex, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024226872-A2 | SUBSTITUTED BICYCLIC HETEROCYCLE COMPOUNDS, COMPOSITIONS, AND USES THEREOF | Lakewood Amedex, Inc. (US) | 2024-10-31 | — | — | WO | disclosed |