SCHEMBL26667708

SCHEMBL26667708

CCCCOP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)C[C@@H]1OP(=O)(O)OCCCC

nearest known ligand 0.64

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.57
▸ P2RY1 P47900 3/20 0.55
▸ ENPP1 P22413 2/20 0.55
▸ RNASEL Q05823 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17972805 0.96 POLB (0.55) POLBP2RY1ENPP1
SCHEMBL12402216 0.91 POLB (0.55) POLBP2RY1ENPP1RNASEL
SCHEMBL31309537 0.91 POLB (0.70) POLBP2RY1ENPP1
SCHEMBL17972744 0.90 POLB (0.55) POLBP2RY1ENPP1
SCHEMBL17122136 0.87 POLB (0.56) POLBP2RY1ENPP1RNASEL
SCHEMBL31454757 0.87 POLB (0.70) POLBP2RY1ENPP1RNASEL
SCHEMBL29382612 0.87 POLB (0.70) POLBP2RY1ENPP1RNASEL
SCHEMBL25786818 0.87 POLB (0.59) POLBP2RY1ENPP1
SCHEMBL21447399 0.86 POLB (0.56) POLBP2RY1ENPP1RNASEL
SCHEMBL10034040 0.85 POLB (0.72) POLBP2RY1ENPP1RNASEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399355-A1 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF Lakewood Amedex, Inc. 2023-12-14 — — US disclosed
US-11795192-B2 Antimicrobial compounds, compositions, and uses thereof Lakewood Amedex, Inc. (US) 2023-10-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11795192-B2 Antimicrobial compounds, compositions, and uses thereof CAT, MPO, NISCH POLB 501/4885P2RY1 3076/4885ENPP1 1330/4885
US-20230399355-A1 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF CAT, MPO, NISCH POLB 501/4885P2RY1 3076/4885ENPP1 1330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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