Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 4/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25360994 | 0.83 | KDM4E (0.54) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL535539 | 0.83 | KDM4E (0.51) | KDM4EALDH1A1HPGDPOLBL3MBTL1 | |
| SCHEMBL26040460 | 0.83 | KDM4E (0.54) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL31039239 | 0.83 | KDM4E (0.51) | KDM4EALDH1A1HPGDPOLBL3MBTL1 | |
| SCHEMBL29076894 | 0.81 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL1890350 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL31264177 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL12647217 | 0.79 | SMN1; SMN2 (0.52) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL31310092 | 0.79 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL31447313 | 0.78 | KDM4E (0.52) | KDM4EALDH1A1HPGDPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120476110-B | Nitrogen-containing heterocyclic derivative inhibitor, preparation method and application thereof | SHANGHAI HANSOH BIOMEDICAL Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-119264042-A | Cyclopentane derivative-containing inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2025-01-07 | — | — | CN | disclosed |