Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | IAPP | P10997 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.42 |
| ▸ | JUN | P05412 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TFEB | P19484 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12569874 | 1.00 | MAPT (0.63) | MAPTLMNAKDM4EIAPPGLA | |
| SCHEMBL14441077 | 0.85 | MAPT (0.76) | MAPTLMNAKDM4EIAPPGLA | |
| SCHEMBL181650 | 0.83 | NFE2L2 (0.61) | MAPTLMNAKDM4ETDP1ATM | |
| SCHEMBL1000978 | 0.82 | NFKB1 (0.62) | MAPTLMNAKDM4ENFE2L2NFKB1 | |
| SCHEMBL30686188 | 0.82 | NFKB1 (0.62) | MAPTLMNAKDM4ENFE2L2NFKB1 | |
| SCHEMBL27515562 | 0.82 | PTPN1 (0.45) | MAPTLMNAKDM4ENFE2L2NFKB1 | |
| SCHEMBL29913492 | 0.82 | PTPN1 (0.45) | MAPTLMNAKDM4ENFE2L2NFKB1 | |
| SCHEMBL15941356 | 0.82 | PTPN1 (0.45) | MAPTLMNAKDM4ENFE2L2NFKB1 | |
| SCHEMBL613719 | 0.82 | NFKB1 (0.62) | MAPTLMNAKDM4ENFE2L2NFKB1 | |
| SCHEMBL613718 | 0.82 | NFKB1 (0.62) | MAPTLMNAKDM4ENFE2L2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118930470-B | Synthesis method for constructing N-carboxyl indole by copper-catalyzed alpha, beta-unsaturated ketone C-C bond cleavage | 山东石油化工学院 | 2025-01-24 | — | — | CN | disclosed |
| CN-118930470-A | Synthesis method for constructing N-carboxyl indole by copper-catalyzed alpha, beta-unsaturated ketone C-C bond cleavage | 山东石油化工学院 | 2024-11-12 | — | — | CN | disclosed |