Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 5/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 5/20 | 0.44 |
| ▸ | DRD4 | P21917 | 15/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 15/20 | 0.40 |
| ▸ | DRD3 | P35462 | 6/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.40 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3131468 | 0.87 | SLC6A2 (0.47) | CARM1PRMT6DRD4SIGMAR1DRD3 | |
| SCHEMBL3122265 | 0.74 | KIF11 (0.39) | CARM1PRMT6DRD4SIGMAR1DRD3 | |
| SCHEMBL26933596 | 0.70 | KDM1A (0.47) | DRD4SIGMAR1 | |
| SCHEMBL26933602 | 0.70 | KDM1A (0.47) | DRD4SIGMAR1 | |
| SCHEMBL30636293 | 0.70 | KDM1A (0.47) | DRD4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL30636281 | 0.69 | KDM1A (0.46) | DRD4SIGMAR1 | |
| SCHEMBL29277445 | 0.69 | MGLL (0.41) | DRD4 | |
| SCHEMBL3129510 | 0.67 | CARM1 (0.50) | CARM1PRMT6DRD4SIGMAR1DRD3 | |
| SCHEMBL25738425 | 0.67 | KIF11 (0.50) | DRD4 | |
| SCHEMBL30754900 | 0.65 | CARM1 (0.60) | CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022055-A2 | INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | AMGEN INC. (US) | 2010-02-25 | — | — | WO | disclosed |