Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 6/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 2/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2621737 | 0.86 | ALDH1A1 (0.41) | SMN1; SMN2MAPTNPC1ALDH1A1MEN1 | |
| SCHEMBL29414488 | 0.86 | ALDH1A1 (0.41) | SMN1; SMN2MAPTNPC1ALDH1A1MEN1 | |
| SCHEMBL29414465 | 0.79 | GBA1 (0.53) | SMN1; SMN2MAPTNPC1ALDH1A1MEN1 | |
| SCHEMBL2621733 | 0.78 | EGFR (0.45) | SMN1; SMN2MAPTNPC1ALDH1A1MEN1 | |
| SCHEMBL31314984 | 0.77 | BACE1 (0.53) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL26789623 | 0.77 | BACE1 (0.53) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5435508 | 0.77 | RAB9A (0.49) | SMN1; SMN2MAPTNPC1ALDH1A1MEN1 | |
| SCHEMBL2621735 | 0.76 | ATM (0.40) | — | |
| SCHEMBL23247980 | 0.76 | NCF1 (0.43) | SMN1; SMN2MAPTNPC1ALDH1A1MEN1 | |
| SCHEMBL2621750 | 0.75 | POLB (0.62) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119451968-A | Macrocyclic compounds and uses thereof | 西普拉里斯有限公司 | 2025-02-14 | — | — | CN | disclosed |