Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14176970 | 0.80 | MPO (0.37) | IDO1 | |
| SCHEMBL5254080 | 0.77 | GPR84 (0.37) | CES2CES1GPR84 | |
| SCHEMBL3163556 | 0.74 | TAAR1 (0.43) | IDO1CES2CES1 | |
| SCHEMBL17552649 | 0.72 | CES2 (0.32) | CES2CES1GPR84 | |
| SCHEMBL147453 | 0.72 | CES2 (0.32) | CES2CES1GPR84 | |
| SCHEMBL169957 | 0.72 | F2RL1 (0.33) | CES2CES1GPR84 | |
| SCHEMBL622777 | 0.72 | TAAR1 (0.37) | CES2CES1 | |
| SCHEMBL4674482 | 0.72 | CES2 (0.32) | CES2CES1GPR84 | |
| SCHEMBL322232 | 0.72 | CES2 (0.32) | CES2CES1GPR84 | |
| SCHEMBL10472581 | 0.72 | TAAR1 (0.32) | CES2CES1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2204365-A1 | ALKYLSULFONE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-07-07 | — | — | EP | disclosed |