Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | STS | P08842 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 6/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | VEGFA | P15692 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17848504 | 0.88 | NR1H2 (0.45) | CYP11B2HTTUSP30ALDH1A1SCD5 | |
| SCHEMBL17848673 | 0.87 | USP30 (0.48) | DRD2CYP11B2USP30SCD5 | |
| SCHEMBL17848342 | 0.84 | ALDH1A1 (0.57) | MEN1KMT2ACYP11B2SMN1; SMN2ALDH1A1 | |
| SCHEMBL31117881 | 0.81 | MEN1 (0.53) | MEN1KMT2ASTSHTTSMN1; SMN2 | |
| SCHEMBL17848728 | 0.81 | NR1H2 (0.44) | MEN1KMT2ACYP11B2HTTUSP30 | |
| SCHEMBL23311683 | 0.80 | HDAC2 (0.49) | MEN1KMT2AALDH1A1 | |
| SCHEMBL17848649 | 0.80 | NR1H2 (0.47) | HTTALDH1A1 | |
| SCHEMBL26246633 | 0.80 | RORC (0.46) | ALDH1A1 | |
| SCHEMBL25289227 | 0.79 | MEN1 (0.43) | MEN1KMT2ACYP11B2SMN1; SMN2USP30 | |
| SCHEMBL17848609 | 0.79 | GPR119 (0.50) | STSCYP11B2SMN1; SMN2USP30ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025010311-A1 | UREA-CONTAINING AGONISTS OF OREXIN RECEPTOR TYPE 2 | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-01-09 | — | — | WO | disclosed |